SMOKING-ASSOCIATED GENE EXPRESSION ALTERATIONS IN NASAL EPITHELIUM REVEAL IMMUNE IMPAIRMENT LINKED TO LUNG CANCER RISK

Smoking-associated gene expression alterations in nasal epithelium reveal immune impairment linked to lung cancer risk

Abstract Background Lung cancer is the leading cause of cancer-related death in the world.In contrast to many other cancers, a direct connection to modifiable lifestyle risk in the form of tobacco smoke has long been established.More than 50% of all smoking-related lung cancers occur in former smokers, 40% of which occur more than 15 years after sm

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Effectiveness of DArTseq markers application in genetic diversity and population structure of indigenous chickens in Eastern Province of Rwanda

Abstract Background The application of biotechnologies which make use of genetic markers in chicken breeding is developing rapidly.Diversity Array Technology (DArT) is one of the current Genotyping-By-Sequencing techniques allowing the discovery of whole genome sequencing.In livestock, DArT has been applied in cattle, sheep, and horses.Currently, t

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Intracranial Fungal Granulomas Mimicking High Grade Gliomas. A Decisive Role of Squash Cytology (SC): A Report of Two Cases

Intracranial fungal granulomas can be misdiagnosed clinically and radiologically as neoplastic lesions.They also rarely occur without any history of immunodeficiency or diabetes.We report two such cases of fungal granulomas that were unsuspected clinically and radiologically but were detected on intraoperative squash cytology (SC) and later confirm

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